Treponema Pallidium Hemagglutination Assay (TPHA)

The Treponema Pallidum Hemagglutination Assay (TPHA) is a specific diagnostic blood test used to detect antibodies against Treponema pallidum, the bacterium responsible for causing syphilis. TPHA is primarily used as a confirmatory test. When initial, non-specific screening tests (like VDRL or RPR) come back positive, the TPHA is ordered to confirm whether the infection is truly syphilis.